6BCB
A Complex between PH Domain of p114RhoGEF and Activated RhoA Bound to a GTP Analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | F | Transforming protein RhoA | polymer | 185 | 20865.9 | 1 | UniProt (P61586) Pfam (PF00071) In PDB | Homo sapiens (Human) | Rho cDNA clone 12,h12 |
| 2 | A | Rho guanine nucleotide exchange factor 18 | polymer | 146 | 16780.5 | 1 | UniProt (Q6P9R4) Pfam (PF17838) In PDB | Mus musculus (Mouse) | |
| 3 | F | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (GSP) | |||
| 4 | F | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | F | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | water | water | 18.0 | 431 | Chemie (HOH) |
Sequence modifications
F: 1 - 181 (UniProt: P61586)
A: 302 - 444 (UniProt: Q6P9R4)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ile -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Asp 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 299 | - | expression tag |
| Ile 300 | - | expression tag |
| His 301 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37646.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 625.6 | |
| All* | Total formula weight | 38272.0 |
