6BCA
A Complex between PH Domain of LbcRhoGEF (AKAP-Lbc) and Activated RhoA Bound to a GTP Analog
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | F, C | Transforming protein RhoA | polymer | 185 | 20865.9 | 2 | UniProt (P61586) Pfam (PF00071) In PDB | Homo sapiens (Human) | Rho cDNA clone 12,h12 |
2 | A, B | A-kinase anchor protein 13 | polymer | 151 | 17491.3 | 2 | UniProt (Q12802) Pfam (PF00169) In PDB | Homo sapiens (Human) | AKAP-13,AKAP-Lbc,Breast cancer nuclear receptor-binding auxiliary protein,Guanine nucleotide exchange factor Lbc,Human thyroid-anchoring protein 31,Lymphoid blast crisis oncogene,LBC oncogene,Non-oncogenic Rho GTPase-specific GTP exchange factor,Protein kinase A-anchoring protein 13,PRKA13,p47 |
3 | F, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | F, C | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | non-polymer | 539.2 | 2 | Chemie (GSP) | |||
5 | water | water | 18.0 | 487 | Chemie (HOH) |
Sequence modifications
F, C: 1 - 181 (UniProt: P61586)
A, B: 2193 - 2333 (UniProt: Q12802)
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ile -2 | - | expression tag |
Leu -1 | - | expression tag |
Asp 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 2189 | - | expression tag |
Ile 2190 | - | expression tag |
Leu 2191 | - | expression tag |
Asp 2192 | - | expression tag |
His 2334 | - | expression tag |
His 2335 | - | expression tag |
His 2336 | - | expression tag |
His 2337 | - | expression tag |
His 2338 | - | expression tag |
His 2339 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 76714.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1127.1 | |
All* | Total formula weight | 77841.6 |