6BBI
The CRAC channel Orai in an unlatched-closed conformation; K163W loss-of-function mutation; P42212 crystal form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Calcium release-activated calcium channel protein 1 | polymer | 214 | 24284.3 | 3 | UniProt (Q9U6B8) Pfam (PF07856) In PDB | Drosophila melanogaster (Fruit fly) | Protein orai,dOrai |
Sequence modifications
A, B, C: 133 - 341 (UniProt: Q9U6B8)
| PDB | External Database | Details |
|---|---|---|
| Trp 163 | Lys 163 | engineered mutation |
| Ser 224 | Cys 224 | engineered mutation |
| Thr 283 | Cys 283 | engineered mutation |
| Glu 342 | - | expression tag |
| Gly 343 | - | expression tag |
| Glu 344 | - | expression tag |
| Glu 345 | - | expression tag |
| Phe 346 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 72852.8 | |
| All* | Total formula weight | 72852.8 |
