6BAD
Lactate Dehydrogenase in complex with inhibitor (R)-3-((2-chlorophenyl)thio)-6-(3-((4-fluorophenyl)amino)phenyl)-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | L-lactate dehydrogenase A chain | polymer | 331 | 36603.5 | 4 | UniProt (P00338) Pfam (PF00056) Pfam (PF02866) | Homo sapiens (Human) | LDH-A,Cell proliferation-inducing gene 19 protein,LDH muscle subunit,LDH-M,Renal carcinoma antigen NY-REN-59 |
| 2 | E, J, O, V (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, G, K, L, P... (A, B, C) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 7 | Chemie (EPE) | |||
| 4 | H, M, R, S, W (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | I, N, U, X (A, B, C, D) | (6R)-3-[(2-chlorophenyl)sulfanyl]-6-{3-[(4-fluorophenyl)amino]phenyl}-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one | non-polymer | 524.0 | 4 | Chemie (D0Y) | |||
| 6 | AA, BA, Y, Z (C, D, A, B) | water | water | 18.0 | 751 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 146413.9 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 6898.3 | |
| All* | Total formula weight | 153312.1 |
