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6BAB

The structure of human CamKII with bound inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DCalcium/calmodulin-dependent protein kinase type II subunit deltapolymer30234459.64UniProt (Q6PHZ2)
Pfam (PF00069)
In PDB
Mus musculus (Mouse)CaMK-II subunit delta
2A, B, C, DN-[(2S)-2-(diethylamino)propyl]-2-(3-hydroxyazetidin-1-yl)-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamidenon-polymer505.64Chemie (D0S)
3A, B, CL(+)-TARTARIC ACIDnon-polymer150.13Chemie (TLA)
4waterwater18.0936Chemie (HOH)
Sequence modifications
A, B, C, D: 4 - 302 (UniProt: Q6PHZ2)
PDBExternal DatabaseDetails
Gly 1-expression tag
His 2-expression tag
Met 3-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight137838.3
Non-Polymers*Number of molecules7
Total formula weight2472.8
All*Total formula weight140311.1
*Water molecules are not included.

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PDB entries from 2024-07-17

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