6BAB
The structure of human CamKII with bound inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Calcium/calmodulin-dependent protein kinase type II subunit delta | polymer | 302 | 34459.6 | 4 | UniProt (Q6PHZ2) Pfam (PF00069) | Mus musculus (Mouse) | CaMK-II subunit delta |
| 2 | E, G, I, K (A, B, C, D) | N-[(2S)-2-(diethylamino)propyl]-2-(3-hydroxyazetidin-1-yl)-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide | non-polymer | 505.6 | 4 | Chemie (D0S) | |||
| 3 | F, H, J (A, B, C) | L(+)-TARTARIC ACID | non-polymer | 150.1 | 3 | Chemie (TLA) | |||
| 4 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 936 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 4 - 302 (UniProt: Q6PHZ2)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| His 2 | - | expression tag |
| Met 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 137838.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2472.8 | |
| All* | Total formula weight | 140311.1 |
