6B9M
Crystal structure of UHRF1 TTD domain in complex with the polybasic region
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | E3 ubiquitin-protein ligase UHRF1 | polymer | 153 | 17779.0 | 3 | UniProt (E7EZF3) Pfam (PF12148) | Danio rerio (Zebrafish) | RING-type E3 ubiquitin transferase UHRF1,Ubiquitin-like PHD and RING finger domain-containing protein 1,Ubiquitin-like-containing PHD and RING finger domains protein 1 |
| 2 | D (D) | E3 ubiquitin-protein ligase UHRF1 | polymer | 41 | 4341.0 | 1 | UniProt (Q96T88) | Homo sapiens (Human) | Inverted CCAAT box-binding protein of 90 kDa,Nuclear protein 95,Nuclear zinc finger protein Np95,hNp95,RING finger protein 106,RING-type E3 ubiquitin transferase UHRF1,Transcription factor ICBP90,Ubiquitin-like PHD and RING finger domain-containing protein 1,hUHRF1,Ubiquitin-like-containing PHD and RING finger domains protein 1 |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 535 | Chemie (HOH) |
Sequence modifications
A, B, C: 129 - 280 (UniProt: E7EZF3)
| PDB | External Database | Details |
|---|---|---|
| Ser 128 | - | expression tag |
| Pro 171 | Ala 171 | SEE REMARK 999 |
| Glu 173 | Asp 173 | SEE REMARK 999 |
| Arg 207 | His 207 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57678.0 | |
| All* | Total formula weight | 57678.0 |
