6B8J
Co-structure of human glycogen synthase kinase beta with a selective (5-imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Glycogen synthase kinase-3 beta | polymer | 420 | 46881.2 | 1 | UniProt (P49841) Pfam (PF00069) In PDB | Homo sapiens (Human) | GSK-3 beta,Serine/threonine-protein kinase GSK3B |
2 | C | VAL-SEP-ARG-ARG | polymer | 4 | 598.6 | 1 | Homo sapiens | ||
3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
4 | A | CHIR99021 | non-polymer | 465.3 | 1 | Chemie (65C) | |||
5 | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 47479.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 557.4 | |
All* | Total formula weight | 48037.2 |