6B7H

Structure of mGluR3 with an agonist

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Metabotropic glutamate receptor 3	polymer	517	58776.6	1	UniProt (Q14832) Pfam (PF01094)	Homo sapiens (Human)	mGluR3
2	B, C (B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
3	D (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
4	E (A)	(1S,2S,4S,5R,6S)-2-amino-4-[(3-methoxybenzene-1-carbonyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid	non-polymer		334.3	1	Chemie (CWY)
5	F (A)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
6	G (A)	water	water		18.0	14	Chemie (HOH)

Sequence modifications

A: 2 - 507 (UniProt: Q14832)

PDB	External Database	Details
Met -1	-	expression tag
Ala 0	-	expression tag
Leu 1	-	expression tag
Ser 240	Cys 240	conflict
Glu 508	-	expression tag
Gly 509	-	expression tag
His 510	-	expression tag
His 511	-	expression tag
His 512	-	expression tag
His 513	-	expression tag
His 514	-	expression tag
His 515	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	58776.6
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	3
	Total formula weight	595.6
All*	Total formula weight	60221.0

*Water molecules are not included.