6B4E

Crystal structure of Saccharomyces cerevisiae Gle1 CTD-Nup42 GBM complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Nucleoporin GLE1	polymer	296	34258.7	2	UniProt (Q12315) Pfam (PF07817)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Nuclear pore protein GLE1,RNA export factor GLE1
2	C, D (C, D)	Nucleoporin NUP42	polymer	39	4076.7	2	UniProt (P49686)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Nuclear pore protein NUP42
3	E, F (A)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	G, H (A, D)	PROLINE	non-polymer		115.1	2	Chemie (PRO)
5	I, J, K, L (B, A, C, D)	water	water		18.0	628	Chemie (HOH)

Sequence modifications

B, A: 243 - 538 (UniProt: Q12315)

PDB	External Database	Details
Met 243	Val 243	expression tag

C, D: 397 - 430 (UniProt: P49686)

PDB	External Database	Details
Gly 392	-	expression tag
Pro 393	-	expression tag
Ser 394	-	expression tag
Gly 395	-	expression tag
Ser 396	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	76670.8
Non-Polymers*	Number of molecules	4
	Total formula weight	354.4
All*	Total formula weight	77025.2

*Water molecules are not included.