6B31
Structure of RORgt in complex with a novel inverse agonist 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nuclear receptor ROR-gamma | polymer | 228 | 26615.8 | 2 | UniProt (P51449) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | C, D (A, B) | (3S)-N~1~-(3-chloro-4-cyanophenyl)-N~5~-(1,3-diethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-6-yl)-3-methylpentanediamide | non-polymer | 496.0 | 2 | Chemie (CFJ) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53231.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 991.9 | |
| All* | Total formula weight | 54223.6 |
