6B1L

Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001173

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glycylpeptide N-tetradecanoyltransferase	polymer	405	47250.9	2	UniProt (A5K1A2) Pfam (PF01233) Pfam (PF02799)	Plasmodium vivax (strain Salvador I)	PlviB.18219.a.FR2
2	C (A)	TETRADECANOYL-COA	non-polymer		977.9	1	Chemie (MYA)
3	D (A)	1-(5-fluoro-2-{methyl[3-(methylamino)propyl]amino}pyrimidin-4-yl)-N-[(imidazo[1,2-a]pyridin-3-yl)methyl]azetidine-3-carboxamide	non-polymer		426.5	1	Chemie (CJ4)
4	E, F (A, B)	water	water		18.0	186	Chemie (HOH)

Sequence modifications

A, B: 27 - 410 (UniProt: A5K1A2)

PDB	External Database	Details
Met 6	-	expression tag
Gly 7	-	expression tag
Ser 8	-	expression tag
Ser 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
Ser 16	-	expression tag
Ala 17	-	expression tag
Ala 18	-	expression tag
Leu 19	-	expression tag
Glu 20	-	expression tag
Val 21	-	expression tag
Leu 22	-	expression tag
Phe 23	-	expression tag
Gln 24	-	expression tag
Gly 25	-	expression tag
Pro 26	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	94501.9
Non-Polymers*	Number of molecules	2
	Total formula weight	1404.4
All*	Total formula weight	95906.3

*Water molecules are not included.