6B1G
Solution structure of TDP-43 N-terminal domain dimer.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | TAR DNA-binding protein 43, S48E Mutant | polymer | 83 | 9244.3 | 1 | UniProt (Q13148) Pfam (PF18694) In PDB | Homo sapiens (Human) | TDP-43 |
2 | B | TAR DNA-binding protein 43, Y4R Mutant | polymer | 83 | 9196.3 | 1 | UniProt (Q13148) Pfam (PF18694) In PDB | Homo sapiens (Human) | TDP-43 |
Sequence modifications
A: 1 - 80 (UniProt: Q13148)
B: 101 - 180 (UniProt: Q13148)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
His -1 | - | expression tag |
Met 0 | - | expression tag |
Glu 48 | Ser 48 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 98 | - | expression tag |
His 99 | - | expression tag |
Met 100 | - | expression tag |
Arg 104 | Tyr 4 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 18440.7 | |
All* | Total formula weight | 18440.7 |