6B1G

Solution structure of TDP-43 N-terminal domain dimer.

Spectrometer

Experimental method: SOLUTION NMR

Spectrometer ID	Spectrometer maker	Spectrometer model	Spectrometer type	Spectrometer field strength
1	Bruker	AVANCE III HD		850
2	Bruker	AVANCE II		500

Experiment

experiment id	conditions id	solution id	Experiment type
1	1	1	2D 1H-15N HSQC
10	1	2	hbCBcgcdceHE
11	1	1	hbCBcgcdceHE
12	1	2	hbCBcgcdHD
13	1	1	hbCBcgcdHD
14	1	2	3D HCCH-COSY
15	1	1	3D HCCH-COSY
16	1	2	3D HBHA(CO)NH
17	1	1	3D HBHA(CO)NH
18	1	2	3D CBCA(CO)NH
19	1	1	3D CBCA(CO)NH
2	1	2	2D 1H-15N HSQC
20	1	2	3D HNCA
21	1	1	3D HNCA
22	1	2	3D HNCO
23	1	1	3D CCH-TOCSY
24	1	2	3D CCH-TOCSY
25	1	2	3D 1H-13C NOESY aromatic
26	1	1	3D 1H-13C NOESY aromatic
27	1	2	3D 1H-13C NOESY aliphatic
28	1	1	3D Filtered 1H-15N NOESY
29	1	2	3D Filtered 1H-13C NOESY
3	1	1	2D 1H-13C HSQC
30	1	2	3D Filtered 1H-15N NOESY
4	1	2	2D 1H-13C HSQC
5	1	1	3D HNCO
6	1	1	3D Filtered 1H-13C NOESY
7	1	2	3D 1H-15N NOESY
8	1	1	3D 1H-15N NOESY
9	1	1	3D 1H-13C NOESY aliphatic

NMR Sample

conditions id	NMR sample pH	NMR sample pressure	NMR sample temperature
1	6.8	1	298

Conformers

Conformers Calculated Total Number	200
Conformers Submitted Total Number	20