6B0E

Crystal structure of Pfs25 in complex with the transmission blocking antibody 1260

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	1260 antibody, light chain	polymer	219	23980.7	1		Homo sapiens (Human)
2	B (B)	1260 antibody, heavy chain	polymer	227	24567.4	1		Homo sapiens (Human)
3	C (E)	25 kDa ookinete surface antigen	polymer	183	20104.2	1	UniProt (P13829) Pfam (PF06247)	Plasmodium falciparum (isolate NF54)	Pfs25

Sequence modifications

E: 1 - 172 (UniProt: P13829)

PDB	External Database	Details
Thr -1	-	expression tag
Gly 0	-	expression tag
Gln 91	Asn 112	engineered mutation
Gln 144	Asn 165	engineered mutation
Gln 166	Asn 187	engineered mutation
Gly 173	-	expression tag
Thr 174	-	expression tag
Lys 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag
His 178	-	expression tag
His 179	-	expression tag
His 180	-	expression tag
His 181	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	68652.2
All*	Total formula weight	68652.2

*Water molecules are not included.