6B09
Crystal structure of HsNUDT16 in complex with diADPR (soaked)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | U8 snoRNA-decapping enzyme | polymer | 195 | 21330.4 | 2 | UniProt (Q96DE0) Pfam (PF22327) | Homo sapiens (Human) | IDP phosphatase,IDPase,Inosine diphosphate phosphatase,Nucleoside diphosphate-linked moiety X motif 16,Nudix motif 16,Nudix hydrolase 16,U8 snoRNA-binding protein H29K,m7GpppN-mRNA hydrolase |
| 2 | C, H (A, B) | [(2~{R},3~{S},4~{S},5~{S})-5-(6-aminopurin-9-yl)-4-[(2~{S},3~{S},4~{S},5~{S})-5-[[[[(2~{R},3~{R},4~{S},5~{S})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]oxy-3-oxidanyl-oxolan-2-yl]methyl phosphono hydrogen phosphate | non-polymer | 968.5 | 2 | Chemie (C7G) | |||
| 3 | D, E, I, J (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | G, K (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | L (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 195 (UniProt: Q96DE0)
| PDB | External Database | Details |
|---|---|---|
| Val 22 | Ala 22 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42660.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2115.7 | |
| All* | Total formula weight | 44776.5 |
