6AX4
Plk-1 polo-box domain in complex with histidine N(tau)-cyclized Macrocycle 5b.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase PLK1 | polymer | 237 | 27285.2 | 1 | UniProt (P53350) Pfam (PF00659) | Homo sapiens (Human) | Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13 |
| 2 | B (C) | histidine N(tau)-cyclized Macrocycle 5b | polymer | 5 | 863.9 | 1 | synthetic construct | ||
| 3 | C (C) | AMYLAMINE | non-polymer | 87.2 | 1 | Chemie (AML) | |||
| 4 | D, E (A, C) | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence modifications
A: 371 - 603 (UniProt: P53350)
| PDB | External Database | Details |
|---|---|---|
| Gly 367 | - | expression tag |
| Ala 368 | - | expression tag |
| His 369 | - | expression tag |
| Met 370 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28149.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 87.2 | |
| All* | Total formula weight | 28236.3 |
