6AU5
Structure of cetuximab with aminoheptanoic acid-linked n-butylarginine meditope variant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | cetuximab Fab light chain | polymer | 213 | 23287.7 | 2 | UniProt (P01834) Pfam (PF07654) In PDB | Mus musculus | |
2 | B, D | cetuximab Fab heavy chain | polymer | 221 | 23725.5 | 2 | UniProt (S6B291) Pfam (PF07686) Pfam (PF07654) In PDB | Mus musculus | |
3 | E, F | meditope | polymer | 11 | 1434.7 | 2 | synthetic construct | ||
4 | B, C, D | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
5 | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 107 (PDB: 6AU5)
A, C: 108 - 213 (UniProt: P01834)
B, D: 1 - 107 (PDB: 6AU5)
B, D: 108 - 221 (UniProt: S6B291)
A, C: 108 - 213 (UniProt: P01834)
PDB | External Database | Details |
---|---|---|
Ala 213 | Glu 106 | conflict |
B, D: 108 - 221 (UniProt: S6B291)
PDB | External Database | Details |
---|---|---|
Ala 119 | Ser 136 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 96895.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 288.2 | |
All* | Total formula weight | 97184.1 |