6ASZ

Chromodomain HP1 with Y24F mutation bound to histone H3 peptide containing trimethyl lysine

Replaces:  5KOG

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Heterochromatin protein 1	polymer	69	8570.5	1	UniProt (P05205) Pfam (PF00385)	Drosophila melanogaster (Fruit fly)	HP1,Non-histone chromosomal protein C1A9 antigen
2	B (P)	trimethyl lysine histone H3 tail peptide	polymer	6	733.9	1	UniProt (by SIFTS) (P02299)	Drosophila melanogaster
3	C, D (A, P)	water	water		18.0	19	Chemie (HOH)

Sequence modifications

A: 17 - 76 (UniProt: P05205)

PDB	External Database	Details
Met 8	-	initiating methionine
Lys 9	-	expression tag
Lys 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
Phe 24	Tyr 24	engineered mutation
Met 38	Lys 38	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	9304.3
All*	Total formula weight	9304.3

*Water molecules are not included.