6AQH

Crystal Structure of Lysyl-tRNA Synthetase from Mycobacterium thermoresistibile complexed with L-lysine and Cladosporin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Lysine--tRNA ligase	polymer	508	56988.5	4	UniProt (G7CF12) Pfam (PF01336) Pfam (PF00152)	Mycobacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 / 316)	Lysyl-tRNA synthetase,LysRS
2	E, G, K, M (A, B, C, D)	LYSINE	non-polymer		147.2	4	Chemie (LYS)
3	F, H, L, N (A, B, C, D)	cladosporin	non-polymer		292.3	4	Chemie (KRS)
4	I, J (B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5	O, P, Q, R (A, B, C, D)	water	water		18.0	272	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 500 (UniProt: G7CF12)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	227954.0
Non-Polymers*	Number of molecules	10
	Total formula weight	1882.2
All*	Total formula weight	229836.2

*Water molecules are not included.