6AQG

Crystal Structure of Lysyl-tRNA Synthetase from Mycobacterium ulcerans complexed with L-lysine and Cladosporin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Lysine--tRNA ligase	polymer	506	56581.6	4	UniProt (A0PV47) Pfam (PF01336) Pfam (PF00152) In PDB	Mycobacterium ulcerans (strain Agy99)	Lysyl-tRNA synthetase,LysRS
2	A, B, C, D	LYSINE	non-polymer		147.2	4	Chemie (LYS)
3	A, B, C, D	cladosporin	non-polymer		292.3	4	Chemie (KRS)
4	A, B, C, D	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	9	Chemie (MPD)
5		water	water		18.0	982	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 498 (UniProt: A0PV47)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	226326.5
Non-Polymers*	Number of molecules	17
	Total formula weight	2821.7
All*	Total formula weight	229148.1

*Water molecules are not included.