6APN

HLA-A*0201 single chain trimer with HPV.16 E7 peptide LLMGTLGIV

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta-2-microglobulin--HLA-A*0201--HPV.16 E7 peptide LLMGTLGIV chimera	polymer	446	50091.1	2	UniProt (P61769) UniProt (P01892) Pfam (PF07654) Pfam (PF00129) UniProt (by SIFTS) (P03129) UniProt (by SIFTS) (P04439)	Homo sapiens (Human)	MHC class I antigen A*2,MHC class I antigen A*2
2	C, D (A, B)	water	water		18.0	206	Chemie (HOH)

Sequence modifications

A, B: 1 - 24 (PDB: 6APN)
A, B: 25 - 123 (UniProt: P61769)

PDB	External Database	Details
Gly 124	-	linker
Gly 125	-	linker
Gly 126	-	linker
Gly 127	-	linker
Ser 128	-	linker
Gly 129	-	linker
Gly 130	-	linker
Gly 131	-	linker
Gly 132	-	linker
Ser 133	-	linker
Gly 134	-	linker
Gly 135	-	linker
Gly 136	-	linker
Gly 137	-	linker
Ser 138	-	linker
Gly 139	-	linker
Gly 140	-	linker
Gly 141	-	linker
Gly 142	-	linker
Ser 143	-	linker
Gly 144	-	linker

A, B: 145 - 420 (UniProt: P01892)

PDB	External Database	Details
Ala 227	Tyr 108	conflict
Glu 419	Pro 300	conflict
Asn 420	Ser 301	conflict
Leu 421	-	expression tag
Tyr 422	-	expression tag
Phe 423	-	expression tag
Gln 424	-	expression tag
Gly 425	-	expression tag
His 426	-	expression tag
His 427	-	expression tag
His 428	-	expression tag
His 429	-	expression tag
His 430	-	expression tag
His 431	-	expression tag
Gly 432	-	expression tag
Leu 433	-	expression tag
Asn 434	-	expression tag
Asp 435	-	expression tag
Ile 436	-	expression tag
Phe 437	-	expression tag
Glu 438	-	expression tag
Ala 439	-	expression tag
Gln 440	-	expression tag
Lys 441	-	expression tag
Ile 442	-	expression tag
Glu 443	-	expression tag
Trp 444	-	expression tag
His 445	-	expression tag
Glu 446	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	100182.2
All*	Total formula weight	100182.2

*Water molecules are not included.