6AO5
Crystal structure of human MST2 in complex with SAV1 SARAH domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase 3 | polymer | 362 | 41734.0 | 1 | UniProt (Q13188) Pfam (PF00069) Pfam (PF11629) In PDB | Homo sapiens (Human) | Mammalian STE20-like protein kinase 2,MST-2,STE20-like kinase MST2,Serine/threonine-protein kinase Krs-1 |
| 2 | B | Protein salvador homolog 1 | polymer | 93 | 11271.0 | 1 | UniProt (Q9H4B6) In PDB | Homo sapiens (Human) | 45 kDa WW domain protein,hWW45 |
| 3 | A | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
A: 16 - 313 (UniProt: Q13188)
A: 428 - 491 (UniProt: Q13188)
| PDB | External Database | Details |
|---|---|---|
| Asn 146 | Asp 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53004.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 530.5 | |
| All* | Total formula weight | 53535.4 |
