6AMH
Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB4D11 with Ser bound as E(Aex1)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Tryptophan synthase beta chain 1 | polymer | 396 | 43466.7 | 4 | UniProt (Q8U093) Pfam (PF00291) In PDB | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) | |
2 | A, B, C, D | [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE | non-polymer | 336.2 | 4 | Chemie (PLS) | |||
3 | A, B, C, D | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
4 | water | water | 18.0 | 577 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 388 (UniProt: Q8U093)
PDB | External Database | Details |
---|---|---|
Gly 17 | Glu 17 | engineered mutation |
Val 68 | Ile 68 | engineered mutation |
Ser 274 | Phe 274 | engineered mutation |
Ser 292 | Thr 292 | engineered mutation |
Ala 321 | Thr 321 | engineered mutation |
Leu 389 | - | expression tag |
Glu 390 | - | expression tag |
His 391 | - | expression tag |
His 392 | - | expression tag |
His 393 | - | expression tag |
His 394 | - | expression tag |
His 395 | - | expression tag |
His 396 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 173866.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1436.9 | |
All* | Total formula weight | 175303.7 |