6ALZ
Crystal structure of Protein Phosphatase 1 bound to the natural inhibitor Tautomycetin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | polymer | 299 | 34162.1 | 2 | UniProt (P62136) Pfam (PF16891) Pfam (PF00149) In PDB | Homo sapiens (Human) | PP-1A |
2 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
3 | A, B | (2Z)-2-[(1R)-3-{[(2R,3S,4R,7S,8S,11S,13R,16E)-17-ethyl-4,8-dihydroxy-3,7,11,13-tetramethyl-6,15-dioxononadeca-16,18-dien-2-yl]oxy}-1-hydroxy-3-oxopropyl]-3-methylbut-2-enedioic acid | non-polymer | 624.8 | 2 | Chemie (BKM) | |||
4 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
6 | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence modifications
A, B: 7 - 300 (UniProt: P62136)
PDB | External Database | Details |
---|---|---|
Gly 2 | - | expression tag |
His 3 | - | expression tag |
Met 4 | - | expression tag |
Gly 5 | - | expression tag |
Ser 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 68324.3 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 1689.2 | |
All* | Total formula weight | 70013.5 |