6ALZ
Crystal structure of Protein Phosphatase 1 bound to the natural inhibitor Tautomycetin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | polymer | 299 | 34162.1 | 2 | UniProt (P62136) Pfam (PF16891) Pfam (PF00149) | Homo sapiens (Human) | PP-1A |
| 2 | C, D, J, K (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 3 | E, L (A, B) | (2Z)-2-[(1R)-3-{[(2R,3S,4R,7S,8S,11S,13R,16E)-17-ethyl-4,8-dihydroxy-3,7,11,13-tetramethyl-6,15-dioxononadeca-16,18-dien-2-yl]oxy}-1-hydroxy-3-oxopropyl]-3-methylbut-2-enedioic acid | non-polymer | 624.8 | 2 | Chemie (BKM) | |||
| 4 | F (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | G, H, I, M (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence modifications
A, B: 7 - 300 (UniProt: P62136)
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | - | expression tag |
| His 3 | - | expression tag |
| Met 4 | - | expression tag |
| Gly 5 | - | expression tag |
| Ser 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68324.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1689.2 | |
| All* | Total formula weight | 70013.5 |
