6AL8
Crystal structure HpiC1 Y101F/F138S
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, D, E) | 12-epi-hapalindole C/U synthase | polymer | 225 | 24449.0 | 4 | UniProt (A0A076NBW8) Pfam (PF22825) | Fischerella sp. ATCC 43239 | HpiU5 |
| 2 | E, F, G, I, J... (A, B, D, E) | CALCIUM ION | non-polymer | 40.1 | 9 | Chemie (CA) | |||
| 3 | H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | O (E) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | P (E) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 6 | Q, R, S, T (A, B, D, E) | water | water | 18.0 | 509 | Chemie (HOH) |
Sequence modifications
A, B, D, E: 26 - 227 (UniProt: A0A076NBW8)
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | initiating methionine |
| Gly 4 | - | expression tag |
| Ser 5 | - | expression tag |
| Ser 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| Ser 13 | - | expression tag |
| Ser 14 | - | expression tag |
| Gly 15 | - | expression tag |
| Leu 16 | - | expression tag |
| Val 17 | - | expression tag |
| Pro 18 | - | expression tag |
| Arg 19 | - | expression tag |
| Gly 20 | - | expression tag |
| Ser 21 | - | expression tag |
| His 22 | - | expression tag |
| Met 23 | - | expression tag |
| Ala 24 | - | expression tag |
| Ser 25 | - | expression tag |
| Phe 101 | Tyr 101 | engineered mutation |
| Ser 138 | Phe 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 97796.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 623.0 | |
| All* | Total formula weight | 98419.1 |
