6AL4

CRYSTAL STRUCTURE OF ANTI-CD19 ANTIBODY B43 FAB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	B43 LIGHT CHAIN	polymer	218	23815.3	3	UniProt (Q6P5S8) Pfam (PF07686) Pfam (PF07654)	Homo sapiens (Human)
2	B, D, F (B, D, F)	B43 HEAVY CHAIN	polymer	233	25225.1	3	UniProt (Q6GMX6) Pfam (PF07686) Pfam (PF07654)	Homo sapiens (Human)
3	G, H, I, J, K... (A, B, C, D, E...)	water	water		18.0	330	Chemie (HOH)

Sequence modifications

A, C, E: 1 - 108 (PDB: 6AL4)
A, C, E: 109 - 218 (UniProt: Q6P5S8)
B, D, F: 1 - 113 (PDB: 6AL4)
B, D, F: 114 - 227 (UniProt: Q6GMX6)

PDB	External Database	Details
Thr 119	Leu 130	conflict
His 228	-	expression tag
His 229	-	expression tag
His 230	-	expression tag
His 231	-	expression tag
His 232	-	expression tag
His 233	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	147120.9
All*	Total formula weight	147120.9

*Water molecules are not included.