6AKF
Crystal structure of mouse claudin-3 P134A mutant in complex with C-terminal fragment of Clostridium perfringens enterotoxin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, E, G) | Claudin-3 | polymer | 190 | 19880.5 | 4 | UniProt (Q9Z0G9) Pfam (PF00822) | Mus musculus (Mouse) | |
| 2 | E, F, G, H (B, D, F, H) | Heat-labile enterotoxin B chain | polymer | 119 | 13329.8 | 4 | UniProt (P01558) | Clostridium perfringens |
Sequence modifications
A, C, E, G: 1 - 183 (UniProt: Q9Z0G9)
B, D, F, H: 203 - 319 (UniProt: P01558)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | see sequence details |
| His -5 | - | see sequence details |
| Met -4 | - | see sequence details |
| Ala -3 | - | see sequence details |
| Ser -2 | - | see sequence details |
| Gly -1 | - | see sequence details |
| Ser 0 | - | see sequence details |
| Ala 103 | Cys 103 | engineered mutation |
| Ala 106 | Cys 106 | engineered mutation |
| Ala 134 | Pro 134 | engineered mutation |
| Ala 181 | Cys 181 | engineered mutation |
| Ala 182 | Cys 182 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 201 | - | see sequence details |
| Ser 202 | - | see sequence details |
| Ala 313 | Ser 313 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 132841.2 | |
| All* | Total formula weight | 132841.2 |
