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6AKF

Crystal structure of mouse claudin-3 P134A mutant in complex with C-terminal fragment of Clostridium perfringens enterotoxin

Functional Information from GO Data
ChainGOidnamespacecontents
A0005198molecular_functionstructural molecule activity
A0005923cellular_componentbicellular tight junction
A0016020cellular_componentmembrane
B0005576cellular_componentextracellular region
C0005198molecular_functionstructural molecule activity
C0005923cellular_componentbicellular tight junction
C0016020cellular_componentmembrane
D0005576cellular_componentextracellular region
E0005198molecular_functionstructural molecule activity
E0005923cellular_componentbicellular tight junction
E0016020cellular_componentmembrane
F0005576cellular_componentextracellular region
G0005198molecular_functionstructural molecule activity
G0005923cellular_componentbicellular tight junction
G0016020cellular_componentmembrane
H0005576cellular_componentextracellular region
Functional Information from PROSITE/UniProt
site_idPS01346
Number of Residues16
DetailsCLAUDIN Claudin family signature. GLWmnCvvqstgqm.QC
ChainResidueDetails
AGLY48-CYS63

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues67
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues300
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues188
DetailsTopological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246031

PDB entries from 2025-12-10

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