6AJG
Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with SQ109
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Drug exporters of the RND superfamily-like protein,Endolysin | polymer | 943 | 104007.6 | 1 | UniProt (I7G2R2) UniProt (D9IEF7) Pfam (PF03176) Pfam (PF00959) UniProt (by SIFTS) (A0QP27) In PDB | Mycobacterium smegmatis str. MC2 155 | Lysis protein,Lysozyme,Muramidase |
2 | A | N-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-N'-[(1R,3S,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]ethane-1,2-diamine | non-polymer | 330.6 | 1 | Chemie (3RX) | |||
3 | A | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 9 | Chemie (LMT) | |||
4 | A | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID | non-polymer | 190.2 | 2 | Chemie (MHA) |
Sequence modifications
A: 1 - 748 (UniProt: I7G2R2)
A: 751 - 910 (UniProt: D9IEF7)
PDB | External Database | Details |
---|---|---|
Met -12 | - | expression tag |
Pro -11 | - | expression tag |
Glu -10 | - | expression tag |
Val -9 | - | expression tag |
Val -8 | - | expression tag |
Gly -7 | - | expression tag |
Ser -6 | - | expression tag |
Tyr -5 | - | expression tag |
Phe -4 | - | expression tag |
Gln -3 | - | expression tag |
Ser -2 | - | expression tag |
Asn -1 | - | expression tag |
Ala 0 | - | expression tag |
Glu 749 | - | linker |
Phe 750 | - | linker |
PDB | External Database | Details |
---|---|---|
Thr 803 | Cys 54 | engineered mutation |
Ala 846 | Cys 97 | engineered mutation |
Glu 911 | - | expression tag |
Phe 912 | - | expression tag |
His 913 | - | expression tag |
Leu 914 | - | expression tag |
Gly 915 | - | expression tag |
Gly 916 | - | expression tag |
Ile 917 | - | expression tag |
Lys 918 | - | expression tag |
Ala 919 | - | expression tag |
Phe 920 | - | expression tag |
His 921 | - | expression tag |
His 922 | - | expression tag |
His 923 | - | expression tag |
His 924 | - | expression tag |
His 925 | - | expression tag |
His 926 | - | expression tag |
His 927 | - | expression tag |
His 928 | - | expression tag |
His 929 | - | expression tag |
His 930 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 104007.6 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 5306.4 | |
All* | Total formula weight | 109314.0 |