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6AFX

Proton pyrophosphatase - E225A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Pyrophosphate-energized vacuolar membrane proton pumppolymer76680034.82UniProt (P21616)
Pfam (PF03030)
Vigna radiata var. radiata (Mung bean)Pyrophosphate-energized inorganic pyrophosphatase,H(+)-PPase,Vacuolar H(+)-pyrophosphatase
2C, D, P, Q
(A, B)
PHOSPHATE IONnon-polymer95.04Chemie (PO4)
3E, F, G, H, I...
(A, B)
MAGNESIUM IONnon-polymer24.310Chemie (MG)
4J, W
(A, B)
POTASSIUM IONnon-polymer39.12Chemie (K)
5K, L, M, N, O...
(A, B)
2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOLnon-polymer252.37Chemie (1PG)
6AA, Z
(B, A)
waterwater18.0488Chemie (HOH)
Sequence modifications
A, B: 1 - 766 (UniProt: P21616)
PDBExternal DatabaseDetails
Ala 225Glu 225engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight160069.6
Non-Polymers*Number of molecules23
Total formula weight2467.3
All*Total formula weight162536.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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