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6ADC

Crystal structure of the E148A mutant CLC-ec1 in the presence of 50mM bromoacetate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
H(+)/Cl(-) exchange transporter ClcApolymer44247042.82UniProt (P37019)
Pfam (PF00654)
Escherichia coli (strain K12)ClC-ec1
2C, E
(C, E)
antibody Fab fragment, heavy chainpolymer22223823.02Mus musculus
3D, F
(D, F)
antibody Fab fragment, light chainpolymer21123088.42Mus musculus
4G, H
(A, B)
bromoacetic acidnon-polymer138.92Chemie (BXA)
Sequence modifications
A, B: 17 - 458 (UniProt: P37019)
PDBExternal DatabaseDetails
Ala 148Glu 148engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight187908.5
Non-Polymers*Number of molecules2
Total formula weight277.9
All*Total formula weight188186.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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