6AA5
Crystal structure of MTH1 in complex with 3-isomangostin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 7,8-dihydro-8-oxoguanine triphosphatase | polymer | 163 | 18985.6 | 1 | UniProt (P36639) Pfam (PF00293) In PDB | Homo sapiens (Human) | |
| 2 | A | 5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one | non-polymer | 410.5 | 1 | Chemie (MKU) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence modifications
A: 3 - 156 (UniProt: P36639)
| PDB | External Database | Details |
|---|---|---|
| Met 2 | - | initiating methionine |
| Leu 157 | - | expression tag |
| Glu 158 | - | expression tag |
| His 159 | - | expression tag |
| His 160 | - | expression tag |
| His 161 | - | expression tag |
| His 162 | - | expression tag |
| His 163 | - | expression tag |
| His 164 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18985.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 702.8 | |
| All* | Total formula weight | 19688.3 |
