6A9A
Ternary complex crystal structure of dCH with dCMP and THF
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Deoxycytidylate 5-hydroxymethyltransferase | polymer | 246 | 28506.2 | 1 | UniProt (P08773) Pfam (PF00303) | Enterobacteria phage T4 (Bacteriophage T4) | Deoxycytidylate hydroxymethylase,dCMP hydroxymethylase,dCMP HMase |
2 | B (A) | IODIDE ION | non-polymer | 126.9 | 1 | Chemie (IOD) | |||
3 | C (A) | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE | non-polymer | 307.2 | 1 | Chemie (DCM) | |||
4 | D (A) | (6S)-5,6,7,8-TETRAHYDROFOLATE | non-polymer | 445.4 | 1 | Chemie (THG) | |||
5 | E (A) | water | water | 18.0 | 255 | Chemie (HOH) |
Sequence modifications
A: 1 - 246 (UniProt: P08773)
PDB | External Database | Details |
---|---|---|
Ser 148 | Cys 148 | engineered mutation |
Asn 179 | Asp 179 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 28506.2 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 879.5 | |
All* | Total formula weight | 29385.7 |