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6A84

Tankyrase-2 in complex with compound 15d

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATankyrase-2polymer16819150.61UniProt (Q9H2K2)
Pfam (PF00644)
In PDB
Homo sapiens (Human)TANK2,ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-like protein,Tankyrase-related protein
2BTankyrase-2polymer485364.01UniProt (Q9H2K2)
In PDB
Homo sapiens (Human)TANK2,ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-like protein,Tankyrase-related protein
3AZINC IONnon-polymer65.41Chemie (ZN)
4A2-(4-chloro-1,2-dihydro-1'H-spiro[indole-3,4'-piperidin]-1'-yl)-5,6,7,8-tetrahydroquinazolin-4(3H)-onenon-polymer370.91Chemie (9SU)
5APHOSPHATE IONnon-polymer95.01Chemie (PO4)
6AGLYCEROLnon-polymer92.11Chemie (GOL)
7waterwater18.0141Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight24514.7
Non-Polymers*Number of molecules4
Total formula weight623.3
All*Total formula weight25138.0
*Water molecules are not included.

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PDB entries from 2024-07-10

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