6A6I

Crystal structure of the winged-helix domain of Cockayne syndrome group B protein in complex with ubiquitin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G	Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant	polymer	98	11102.5	4	UniProt (Q59FF6) In PDB	Homo sapiens (Human)
2	B, D	Polyubiquitin-B	polymer	76	8604.8	2	UniProt (P0CG47) Pfam (PF00240) In PDB	Homo sapiens (Human)
3	F, H	Polyubiquitin-B	polymer	77	8691.9	2	UniProt (P0CG47) Pfam (PF00240) In PDB	Homo sapiens (Human)
4	B, D, G	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5	C	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6		water	water		18.0	105	Chemie (HOH)

Sequence modifications

A, C, E, G: 1401 - 1493 (UniProt: Q59FF6)

PDB	External Database	Details
Gly 1396	-	expression tag
Pro 1397	-	expression tag
Gly 1398	-	expression tag
His 1399	-	expression tag
Met 1400	-	expression tag

B, D: 1 - 76 (UniProt: P0CG47)

PDB	External Database	Details
Arg 48	Lys 48	engineered mutation

F, H: 1 - 77 (UniProt: P0CG47)

PDB	External Database	Details
Asp 77	Met 77	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	79003.4
Non-Polymers*	Number of molecules	4
	Total formula weight	311.7
All*	Total formula weight	79315.1

*Water molecules are not included.