6A47

Structure of TREX2 in complex with a Y structured dsDNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Three prime repair exonuclease 2	polymer	256	28156.8	2	UniProt (Q9R1A9) Pfam (PF00929)	Mus musculus (Mouse)	3'-5' exonuclease TREX2
2	C, D (C, D)	DNA (5'-D(P*CP*CP*AP*GP*GP*CP*CP*CP*TP*CP*TP*AP*GP*GP*GP*CP*CP*TP*T)-3')	polymer	23	6999.5	2		Mus musculus
3	E, G, H, I (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
4	F (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
5	J, K, L, M (A, B, C, D)	water	water		18.0	314	Chemie (HOH)

Sequence modifications

A, B: 1 - 236 (UniProt: Q9R1A9)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	70312.7
Non-Polymers*	Number of molecules	5
	Total formula weight	120.2
All*	Total formula weight	70432.9

*Water molecules are not included.