6A47
Structure of TREX2 in complex with a Y structured dsDNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006281 | biological_process | DNA repair |
| A | 0008296 | molecular_function | 3'-5'-DNA exonuclease activity |
| A | 0008311 | molecular_function | double-stranded DNA 3'-5' DNA exonuclease activity |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0060090 | molecular_function | molecular adaptor activity |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0006259 | biological_process | DNA metabolic process |
| B | 0006281 | biological_process | DNA repair |
| B | 0008296 | molecular_function | 3'-5'-DNA exonuclease activity |
| B | 0008311 | molecular_function | double-stranded DNA 3'-5' DNA exonuclease activity |
| B | 0008408 | molecular_function | 3'-5' exonuclease activity |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0060090 | molecular_function | molecular adaptor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 301 |
| Chain | Residue |
| A | ASP14 |
| A | GLU16 |
| A | ASP193 |
| C | DT23 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 302 |
| Chain | Residue |
| A | GLU29 |
| A | SER189 |
| A | ALA190 |
| A | GLU191 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 301 |
| Chain | Residue |
| B | GLU16 |
| B | ASP193 |
| D | DT23 |
| B | ASP14 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG C 101 |
| Chain | Residue |
| A | ASP14 |
| A | HOH414 |
| A | HOH437 |
| A | HOH502 |
| C | DT22 |
| C | DT23 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 101 |
| Chain | Residue |
| B | ASP14 |
| B | HOH416 |
| B | HOH448 |
| B | HOH526 |
| D | DT22 |
| D | DT23 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
