6A0I

Crystal structure of human protein N-terminal asparagine amidohydrolase (NTAN1) C75S mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protein N-terminal asparagine amidohydrolase	polymer	318	35778.2	2	UniProt (Q96AB6) Pfam (PF14736) In PDB	Homo sapiens (Human)	Protein NH2-terminal asparagine amidohydrolase,PNAA,Protein NH2-terminal asparagine deamidase,Protein NTN-amidase
2	A, B	GLYCEROL	non-polymer		92.1	22	Chemie (GOL)
3	B, A	PHOSPHATE ION	non-polymer		95.0	3	Chemie (PO4)
4		water	water		18.0	442	Chemie (HOH)

Sequence modifications

A, B: 1 - 310 (UniProt: Q96AB6)

PDB	External Database	Details
Ser 75	Cys 75	engineered mutation
Leu 311	-	expression tag
Glu 312	-	expression tag
His 313	-	expression tag
His 314	-	expression tag
His 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71556.5
Non-Polymers*	Number of molecules	25
	Total formula weight	2311.0
All*	Total formula weight	73867.4

*Water molecules are not included.