6A0I
Crystal structure of human protein N-terminal asparagine amidohydrolase (NTAN1) C75S mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein N-terminal asparagine amidohydrolase | polymer | 318 | 35778.2 | 2 | UniProt (Q96AB6) Pfam (PF14736) | Homo sapiens (Human) | Protein NH2-terminal asparagine amidohydrolase,PNAA,Protein NH2-terminal asparagine deamidase,Protein NTN-amidase |
| 2 | C, D, E, F, G... (A, B) | GLYCEROL | non-polymer | 92.1 | 22 | Chemie (GOL) | |||
| 3 | AA, O, P (B, A) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 4 | BA, CA (A, B) | water | water | 18.0 | 442 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 310 (UniProt: Q96AB6)
| PDB | External Database | Details |
|---|---|---|
| Ser 75 | Cys 75 | engineered mutation |
| Leu 311 | - | expression tag |
| Glu 312 | - | expression tag |
| His 313 | - | expression tag |
| His 314 | - | expression tag |
| His 315 | - | expression tag |
| His 316 | - | expression tag |
| His 317 | - | expression tag |
| His 318 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71556.5 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 2311.0 | |
| All* | Total formula weight | 73867.4 |
