6A04
Structure of pSTING complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Stimulator of interferon genes protein | polymer | 201 | 22833.8 | 2 | UniProt (B8XX90) Pfam (PF15009) | Sus scrofa (Pig) | poSTING,Transmembrane protein 173 |
| 2 | C, D, E, F, G (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | H (B) | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one) | non-polymer | 690.4 | 1 | Chemie (C2E) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
A, B: 152 - 342 (UniProt: B8XX90)
| PDB | External Database | Details |
|---|---|---|
| Ala 150 | - | expression tag |
| Ala 151 | - | expression tag |
| Glu 260 | Gly 260 | conflict |
| Leu 343 | - | expression tag |
| Glu 344 | - | expression tag |
| His 345 | - | expression tag |
| His 346 | - | expression tag |
| His 347 | - | expression tag |
| His 348 | - | expression tag |
| His 349 | - | expression tag |
| His 350 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45667.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1170.7 | |
| All* | Total formula weight | 46838.3 |
