Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002218 | biological_process | activation of innate immune response |
| A | 0032481 | biological_process | positive regulation of type I interferon production |
| B | 0002218 | biological_process | activation of innate immune response |
| B | 0032481 | biological_process | positive regulation of type I interferon production |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 401 |
| Chain | Residue |
| A | ASP205 |
| A | CYS206 |
| A | GLY207 |
| A | ARG220 |
| A | ARG281 |
| A | ARG284 |
| B | ARG220 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | HIS196 |
| A | GLN180 |
| A | ASN183 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | ALA302 |
| A | PRO303 |
| A | GLU304 |
| A | ALA305 |
| A | HOH514 |
| A | HOH523 |
| A | HOH527 |
| A | HOH528 |
| B | GLN180 |
| B | HIS196 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | PRO226 |
| A | GLN227 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 401 |
| Chain | Residue |
| A | HIS332 |
| A | HOH540 |
| B | HIS332 |
| B | GLN335 |
| site_id | AC6 |
| Number of Residues | 29 |
| Details | binding site for residue C2E B 402 |
| Chain | Residue |
| A | SER162 |
| A | GLY166 |
| A | TYR167 |
| A | ILE235 |
| A | ARG238 |
| A | TYR240 |
| A | GLU260 |
| A | THR263 |
| A | PRO264 |
| A | THR267 |
| A | HOH504 |
| A | HOH515 |
| A | HOH520 |
| B | SER162 |
| B | TYR163 |
| B | GLY166 |
| B | TYR167 |
| B | ARG238 |
| B | VAL239 |
| B | TYR240 |
| B | THR241 |
| B | THR263 |
| B | PRO264 |
| B | HOH514 |
| B | HOH530 |
| B | HOH534 |
| B | HOH543 |
| B | HOH546 |
| B | HOH552 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q86WV6","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"Q86WV6","evidenceCode":"ECO:0000250"}]} |
