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5ZXI

Co-crystal structure of an Inhibitor in complex with human PPARdelta LBD

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BPeroxisome proliferator-activated receptor deltapolymer27531430.52UniProt (Q03181)
Pfam (PF00104)
In PDB
Homo sapiens (Human)PPAR-delta,NUCI,Nuclear hormone receptor 1,NUC1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferator-activated receptor beta,PPAR-beta
2A, B6-[2-({2-[4-(furan-2-yl)phenyl]-5-methyl-1H-imidazol-1-yl}methyl)phenoxy]hexanoic acidnon-polymer444.52Chemie (9LU)
3waterwater18.0151Chemie (HOH)
Sequence modifications
A, B: 171 - 441 (UniProt: Q03181)
PDBExternal DatabaseDetails
Gly 167-expression tag
Ser 168-expression tag
His 169-expression tag
Met 170-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight62861.1
Non-Polymers*Number of molecules2
Total formula weight889.0
All*Total formula weight63750.1
*Water molecules are not included.

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PDB entries from 2024-06-12

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