5ZXI
Co-crystal structure of an Inhibitor in complex with human PPARdelta LBD
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0004879 | molecular_function | nuclear receptor activity |
A | 0005634 | cellular_component | nucleus |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
B | 0003677 | molecular_function | DNA binding |
B | 0004879 | molecular_function | nuclear receptor activity |
B | 0005634 | cellular_component | nucleus |
B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | binding site for residue 9LU A 900 |
Chain | Residue |
A | VAL245 |
A | LYS331 |
A | HIS413 |
A | MET417 |
A | LEU433 |
A | TYR437 |
A | HOH1017 |
A | CYS249 |
A | THR252 |
A | THR253 |
A | HIS287 |
A | LEU294 |
A | LEU303 |
A | VAL305 |
A | ILE328 |
site_id | AC2 |
Number of Residues | 16 |
Details | binding site for residue 9LU B 900 |
Chain | Residue |
B | VAL245 |
B | PHE246 |
B | ARG248 |
B | CYS249 |
B | THR252 |
B | THR253 |
B | HIS287 |
B | LEU294 |
B | LEU303 |
B | ILE327 |
B | ILE328 |
B | LYS331 |
B | HIS413 |
B | LEU433 |
B | TYR437 |
B | HOH1013 |