5ZXB

Crystal structure of ACK1 with compound 10d

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Activated CDC42 kinase 1	polymer	275	31423.3	2	UniProt (Q07912) Pfam (PF07714) In PDB	Homo sapiens (Human)	ACK-1,Tyrosine kinase non-receptor protein 2
2	A, B	N-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide	non-polymer		659.7	2	Chemie (9KO)
3		water	water		18.0	93	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	62846.6
Non-Polymers*	Number of molecules	2
	Total formula weight	1319.3
All*	Total formula weight	64165.9

*Water molecules are not included.