5ZXB
Crystal structure of ACK1 with compound 10d
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Activated CDC42 kinase 1 | polymer | 275 | 31423.3 | 2 | UniProt (Q07912) Pfam (PF07714) | Homo sapiens (Human) | ACK-1,Tyrosine kinase non-receptor protein 2 |
| 2 | C, D (A, B) | N-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide | non-polymer | 659.7 | 2 | Chemie (9KO) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62846.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1319.3 | |
| All* | Total formula weight | 64165.9 |
