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5ZUV

Crystal Structure of the Human Coronavirus 229E HR1 motif in complex with pan-CoVs inhibitor EK1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, CSpike glycoprotein,Spike glycoprotein,inhibitor EK1polymer13314690.33UniProt (P15423)
In PDB
Human coronavirus 229E (HCoV-229E)S glycoprotein,E2,Peplomer protein
2A, BCHLORIDE IONnon-polymer35.52Chemie (CL)
3waterwater18.0110Chemie (HOH)
Sequence modifications
A, B, C: 785 - 873 (UniProt: P15423)
PDBExternal DatabaseDetails
Ser 784-expression tag
Ser 874-linker
Gly 875-linker
Gly 876-linker
Arg 877-linker
Gly 878-linker
Gly 879-linker
A, B, C: 880 - 916 (PDB: 5ZUV)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight44071.0
Non-Polymers*Number of molecules2
Total formula weight70.9
All*Total formula weight44141.9
*Water molecules are not included.

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PDB entries from 2024-04-24

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