5ZOL
Crystal structure of a three sites mutantion of FSAA complexed with HA and product
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Fructose-6-phosphate aldolase 1 | polymer | 255 | 26928.0 | 10 | UniProt (P78055) Pfam (PF00923) | Escherichia coli (strain K12) | Fructose-6-phosphate aldolase A,FSAA |
| 2 | AA, EA, HA, K, KA... (F, G, H, A, I...) | 1-hydroxypropan-2-one | non-polymer | 74.1 | 10 | Chemie (4Y8) | |||
| 3 | BA, IA, L, LA, P... (F, H, A, I, B...) | (3S,4S)-3,4-dihydroxy-4-(thiophen-2-yl)butan-2-one | non-polymer | 186.2 | 9 | Chemie (LW2) | |||
| 4 | CA, M, MA, T (F, A, I, C) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | DA, GA, JA, N, NA... (F, G, H, A, I...) | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 6 | FA (G) | thiophene-2-carbaldehyde | non-polymer | 112.2 | 1 | Chemie (LW1) | |||
| 7 | AB, RA, SA, TA, UA... (J, A, B, C, D...) | water | water | 18.0 | 913 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 1 - 220 (UniProt: P78055)
| PDB | External Database | Details |
|---|---|---|
| His -34 | - | expression tag |
| His -33 | - | expression tag |
| His -32 | - | expression tag |
| His -31 | - | expression tag |
| His -30 | - | expression tag |
| His -29 | - | expression tag |
| Ser -28 | - | expression tag |
| Ser -27 | - | expression tag |
| Gly -26 | - | expression tag |
| Leu -25 | - | expression tag |
| Val -24 | - | expression tag |
| Pro -23 | - | expression tag |
| Arg -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Ser -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Met -18 | - | expression tag |
| Lys -17 | - | expression tag |
| Glu -16 | - | expression tag |
| Thr -15 | - | expression tag |
| Ala -14 | - | expression tag |
| Ala -13 | - | expression tag |
| Ala -12 | - | expression tag |
| Lys -11 | - | expression tag |
| Phe -10 | - | expression tag |
| Glu -9 | - | expression tag |
| Arg -8 | - | expression tag |
| Gln -7 | - | expression tag |
| His -6 | - | expression tag |
| Met -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Arg -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Thr 31 | Ile 31 | engineered mutation |
| Thr 59 | Gln 59 | engineered mutation |
| Gln 195 | Ile 195 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 269280.4 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 3535.4 | |
| All* | Total formula weight | 272815.7 |
