5ZOL
Crystal structure of a three sites mutantion of FSAA complexed with HA and product
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005737 | cellular_component | cytoplasm |
A | 0005975 | biological_process | carbohydrate metabolic process |
A | 0006000 | biological_process | fructose metabolic process |
A | 0016829 | molecular_function | lyase activity |
A | 0016832 | molecular_function | aldehyde-lyase activity |
A | 0042182 | biological_process | ketone catabolic process |
A | 0042802 | molecular_function | identical protein binding |
A | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0005975 | biological_process | carbohydrate metabolic process |
B | 0006000 | biological_process | fructose metabolic process |
B | 0016829 | molecular_function | lyase activity |
B | 0016832 | molecular_function | aldehyde-lyase activity |
B | 0042182 | biological_process | ketone catabolic process |
B | 0042802 | molecular_function | identical protein binding |
B | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
C | 0005737 | cellular_component | cytoplasm |
C | 0005975 | biological_process | carbohydrate metabolic process |
C | 0006000 | biological_process | fructose metabolic process |
C | 0016829 | molecular_function | lyase activity |
C | 0016832 | molecular_function | aldehyde-lyase activity |
C | 0042182 | biological_process | ketone catabolic process |
C | 0042802 | molecular_function | identical protein binding |
C | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
D | 0005737 | cellular_component | cytoplasm |
D | 0005975 | biological_process | carbohydrate metabolic process |
D | 0006000 | biological_process | fructose metabolic process |
D | 0016829 | molecular_function | lyase activity |
D | 0016832 | molecular_function | aldehyde-lyase activity |
D | 0042182 | biological_process | ketone catabolic process |
D | 0042802 | molecular_function | identical protein binding |
D | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
E | 0005737 | cellular_component | cytoplasm |
E | 0005975 | biological_process | carbohydrate metabolic process |
E | 0006000 | biological_process | fructose metabolic process |
E | 0016829 | molecular_function | lyase activity |
E | 0016832 | molecular_function | aldehyde-lyase activity |
E | 0042182 | biological_process | ketone catabolic process |
E | 0042802 | molecular_function | identical protein binding |
E | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
F | 0005737 | cellular_component | cytoplasm |
F | 0005975 | biological_process | carbohydrate metabolic process |
F | 0006000 | biological_process | fructose metabolic process |
F | 0016829 | molecular_function | lyase activity |
F | 0016832 | molecular_function | aldehyde-lyase activity |
F | 0042182 | biological_process | ketone catabolic process |
F | 0042802 | molecular_function | identical protein binding |
F | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
G | 0005737 | cellular_component | cytoplasm |
G | 0005975 | biological_process | carbohydrate metabolic process |
G | 0006000 | biological_process | fructose metabolic process |
G | 0016829 | molecular_function | lyase activity |
G | 0016832 | molecular_function | aldehyde-lyase activity |
G | 0042182 | biological_process | ketone catabolic process |
G | 0042802 | molecular_function | identical protein binding |
G | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
H | 0005737 | cellular_component | cytoplasm |
H | 0005975 | biological_process | carbohydrate metabolic process |
H | 0006000 | biological_process | fructose metabolic process |
H | 0016829 | molecular_function | lyase activity |
H | 0016832 | molecular_function | aldehyde-lyase activity |
H | 0042182 | biological_process | ketone catabolic process |
H | 0042802 | molecular_function | identical protein binding |
H | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
I | 0005737 | cellular_component | cytoplasm |
I | 0005975 | biological_process | carbohydrate metabolic process |
I | 0006000 | biological_process | fructose metabolic process |
I | 0016829 | molecular_function | lyase activity |
I | 0016832 | molecular_function | aldehyde-lyase activity |
I | 0042182 | biological_process | ketone catabolic process |
I | 0042802 | molecular_function | identical protein binding |
I | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
J | 0005737 | cellular_component | cytoplasm |
J | 0005975 | biological_process | carbohydrate metabolic process |
J | 0006000 | biological_process | fructose metabolic process |
J | 0016829 | molecular_function | lyase activity |
J | 0016832 | molecular_function | aldehyde-lyase activity |
J | 0042182 | biological_process | ketone catabolic process |
J | 0042802 | molecular_function | identical protein binding |
J | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue 4Y8 A 301 |
Chain | Residue |
A | ASP6 |
A | ASN28 |
A | LYS85 |
A | LW2302 |
site_id | AC2 |
Number of Residues | 7 |
Details | binding site for residue LW2 A 302 |
Chain | Residue |
A | SER166 |
A | 4Y8301 |
A | ASP6 |
A | ASN28 |
A | TYR131 |
A | ASN133 |
A | ARG134 |
site_id | AC3 |
Number of Residues | 2 |
Details | binding site for residue CL A 303 |
Chain | Residue |
A | THR7 |
A | LEU188 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 304 |
Chain | Residue |
A | ALA62 |
A | THR63 |
A | THR64 |
A | HOH445 |
site_id | AC5 |
Number of Residues | 7 |
Details | binding site for residue LW2 B 302 |
Chain | Residue |
B | ASP6 |
B | ASN28 |
B | TYR131 |
B | ARG134 |
B | SER166 |
B | 4Y8301 |
B | HOH407 |
site_id | AC6 |
Number of Residues | 4 |
Details | binding site for residue SO4 B 303 |
Chain | Residue |
B | ALA62 |
B | THR63 |
B | THR64 |
B | GLY67 |
site_id | AC7 |
Number of Residues | 10 |
Details | binding site for residue LW2 C 302 |
Chain | Residue |
C | ASP6 |
C | ASN28 |
C | TYR131 |
C | ASN133 |
C | ARG134 |
C | SER166 |
C | PHE167 |
C | LYS168 |
C | 4Y8301 |
C | HOH468 |
site_id | AC8 |
Number of Residues | 1 |
Details | binding site for residue CL C 303 |
Chain | Residue |
C | ARG76 |
site_id | AC9 |
Number of Residues | 7 |
Details | binding site for residue LW2 D 302 |
Chain | Residue |
D | ASP6 |
D | ASN28 |
D | TYR131 |
D | ARG134 |
D | SER166 |
D | LYS168 |
D | 4Y8301 |
site_id | AD1 |
Number of Residues | 4 |
Details | binding site for residue SO4 D 303 |
Chain | Residue |
D | ALA62 |
D | THR63 |
D | THR64 |
D | GLY67 |
site_id | AD2 |
Number of Residues | 6 |
Details | binding site for residue LW2 E 302 |
Chain | Residue |
E | ASP6 |
E | TYR131 |
E | ASN133 |
E | ARG134 |
E | SER166 |
E | LYS168 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for residue SO4 E 303 |
Chain | Residue |
E | ARG217 |
E | THR218 |
E | SER219 |
F | GLN45 |
site_id | AD4 |
Number of Residues | 6 |
Details | binding site for residue LW2 F 302 |
Chain | Residue |
F | ASP6 |
F | TYR131 |
F | ARG134 |
F | SER166 |
F | LYS168 |
F | HOH419 |
site_id | AD5 |
Number of Residues | 2 |
Details | binding site for residue CL F 303 |
Chain | Residue |
F | THR7 |
F | THR31 |
site_id | AD6 |
Number of Residues | 4 |
Details | binding site for residue SO4 F 304 |
Chain | Residue |
F | ALA62 |
F | THR63 |
F | THR64 |
F | GLY67 |
site_id | AD7 |
Number of Residues | 4 |
Details | binding site for residue LW1 G 302 |
Chain | Residue |
G | ASP6 |
G | ARG134 |
G | SER166 |
G | HOH487 |
site_id | AD8 |
Number of Residues | 5 |
Details | binding site for residue SO4 G 303 |
Chain | Residue |
G | ALA62 |
G | THR63 |
G | THR64 |
G | GLY67 |
G | HOH463 |
site_id | AD9 |
Number of Residues | 5 |
Details | binding site for residue LW2 H 302 |
Chain | Residue |
H | ASP6 |
H | TYR131 |
H | ARG134 |
H | SER166 |
H | HOH470 |
site_id | AE1 |
Number of Residues | 4 |
Details | binding site for residue SO4 H 303 |
Chain | Residue |
H | ALA62 |
H | THR63 |
H | THR64 |
H | GLY67 |
site_id | AE2 |
Number of Residues | 4 |
Details | binding site for residue LW2 I 302 |
Chain | Residue |
I | ASP6 |
I | ARG134 |
I | SER166 |
I | LYS168 |
site_id | AE3 |
Number of Residues | 1 |
Details | binding site for residue CL I 303 |
Chain | Residue |
I | ARG76 |
site_id | AE4 |
Number of Residues | 3 |
Details | binding site for residue SO4 I 304 |
Chain | Residue |
I | ALA62 |
I | THR63 |
I | THR64 |
site_id | AE5 |
Number of Residues | 7 |
Details | binding site for residue LW2 J 302 |
Chain | Residue |
J | ASN28 |
J | TYR131 |
J | ARG134 |
J | SER166 |
J | LYS168 |
J | HOH436 |
J | ASP6 |
site_id | AE6 |
Number of Residues | 4 |
Details | binding site for residue SO4 J 303 |
Chain | Residue |
J | ALA62 |
J | THR63 |
J | THR64 |
J | GLY67 |
site_id | AE7 |
Number of Residues | 13 |
Details | binding site for Di-peptide 4Y8 B 301 and LYS B 85 |
Chain | Residue |
B | ASP6 |
B | THR26 |
B | THR27 |
B | ASN28 |
B | PHE57 |
B | ALA58 |
B | THR59 |
B | VAL60 |
B | VAL83 |
B | VAL84 |
B | VAL86 |
B | LEU107 |
B | LW2302 |
site_id | AE8 |
Number of Residues | 13 |
Details | binding site for Di-peptide 4Y8 C 301 and LYS C 85 |
Chain | Residue |
C | ASP6 |
C | THR27 |
C | ASN28 |
C | PHE57 |
C | ALA58 |
C | THR59 |
C | VAL60 |
C | VAL83 |
C | VAL84 |
C | VAL86 |
C | LEU107 |
C | THR109 |
C | LW2302 |
site_id | AE9 |
Number of Residues | 11 |
Details | binding site for Di-peptide 4Y8 D 301 and LYS D 85 |
Chain | Residue |
D | ASP6 |
D | THR27 |
D | ASN28 |
D | ALA58 |
D | THR59 |
D | VAL60 |
D | VAL83 |
D | VAL84 |
D | VAL86 |
D | LEU107 |
D | LW2302 |
site_id | AF1 |
Number of Residues | 13 |
Details | binding site for Di-peptide 4Y8 E 301 and LYS E 85 |
Chain | Residue |
E | ASP6 |
E | THR26 |
E | THR27 |
E | ASN28 |
E | PHE57 |
E | ALA58 |
E | THR59 |
E | VAL60 |
E | VAL83 |
E | VAL84 |
E | VAL86 |
E | LEU107 |
E | HOH466 |
site_id | AF2 |
Number of Residues | 13 |
Details | binding site for Di-peptide 4Y8 F 301 and LYS F 85 |
Chain | Residue |
F | ASP6 |
F | THR26 |
F | THR27 |
F | ASN28 |
F | PHE57 |
F | ALA58 |
F | THR59 |
F | VAL60 |
F | VAL83 |
F | VAL84 |
F | VAL86 |
F | LEU107 |
F | HOH422 |
site_id | AF3 |
Number of Residues | 12 |
Details | binding site for Di-peptide 4Y8 G 301 and LYS G 85 |
Chain | Residue |
G | ASP6 |
G | THR26 |
G | THR27 |
G | ASN28 |
G | ALA58 |
G | THR59 |
G | VAL60 |
G | VAL83 |
G | VAL84 |
G | VAL86 |
G | LEU107 |
G | HOH437 |
site_id | AF4 |
Number of Residues | 13 |
Details | binding site for Di-peptide 4Y8 H 301 and LYS H 85 |
Chain | Residue |
H | ASP6 |
H | THR26 |
H | THR27 |
H | ASN28 |
H | ALA58 |
H | THR59 |
H | VAL60 |
H | VAL83 |
H | VAL84 |
H | VAL86 |
H | LEU107 |
H | THR109 |
H | HOH442 |
site_id | AF5 |
Number of Residues | 12 |
Details | binding site for Di-peptide 4Y8 I 301 and LYS I 85 |
Chain | Residue |
I | ASP6 |
I | THR26 |
I | THR27 |
I | ASN28 |
I | ALA58 |
I | THR59 |
I | VAL60 |
I | VAL83 |
I | VAL84 |
I | VAL86 |
I | LEU107 |
I | HOH418 |
site_id | AF6 |
Number of Residues | 12 |
Details | binding site for Di-peptide 4Y8 J 301 and LYS J 85 |
Chain | Residue |
J | ASP6 |
J | THR26 |
J | THR27 |
J | ASN28 |
J | PHE57 |
J | ALA58 |
J | THR59 |
J | VAL60 |
J | VAL84 |
J | VAL86 |
J | LEU107 |
J | THR109 |
Functional Information from PROSITE/UniProt
site_id | PS00958 |
Number of Residues | 18 |
Details | TRANSALDOLASE_2 Transaldolase active site. IvVKVPvTaEGLaAiKmL |
Chain | Residue | Details |
A | ILE82-LEU99 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 10 |
Details | ACT_SITE: Schiff-base intermediate with substrate => ECO:0000269|PubMed:11120740, ECO:0000269|PubMed:12051943 |
Chain | Residue | Details |
A | LYS85 | |
J | LYS85 | |
B | LYS85 | |
C | LYS85 | |
D | LYS85 | |
E | LYS85 | |
F | LYS85 | |
G | LYS85 | |
H | LYS85 | |
I | LYS85 |