5ZOL
Crystal structure of a three sites mutantion of FSAA complexed with HA and product
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006000 | biological_process | fructose metabolic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016832 | molecular_function | aldehyde-lyase activity |
| A | 0042182 | biological_process | ketone catabolic process |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006000 | biological_process | fructose metabolic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016832 | molecular_function | aldehyde-lyase activity |
| B | 0042182 | biological_process | ketone catabolic process |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006000 | biological_process | fructose metabolic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016832 | molecular_function | aldehyde-lyase activity |
| C | 0042182 | biological_process | ketone catabolic process |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0006000 | biological_process | fructose metabolic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016832 | molecular_function | aldehyde-lyase activity |
| D | 0042182 | biological_process | ketone catabolic process |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005975 | biological_process | carbohydrate metabolic process |
| E | 0006000 | biological_process | fructose metabolic process |
| E | 0016829 | molecular_function | lyase activity |
| E | 0016832 | molecular_function | aldehyde-lyase activity |
| E | 0042182 | biological_process | ketone catabolic process |
| E | 0042802 | molecular_function | identical protein binding |
| E | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005975 | biological_process | carbohydrate metabolic process |
| F | 0006000 | biological_process | fructose metabolic process |
| F | 0016829 | molecular_function | lyase activity |
| F | 0016832 | molecular_function | aldehyde-lyase activity |
| F | 0042182 | biological_process | ketone catabolic process |
| F | 0042802 | molecular_function | identical protein binding |
| F | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005975 | biological_process | carbohydrate metabolic process |
| G | 0006000 | biological_process | fructose metabolic process |
| G | 0016829 | molecular_function | lyase activity |
| G | 0016832 | molecular_function | aldehyde-lyase activity |
| G | 0042182 | biological_process | ketone catabolic process |
| G | 0042802 | molecular_function | identical protein binding |
| G | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005975 | biological_process | carbohydrate metabolic process |
| H | 0006000 | biological_process | fructose metabolic process |
| H | 0016829 | molecular_function | lyase activity |
| H | 0016832 | molecular_function | aldehyde-lyase activity |
| H | 0042182 | biological_process | ketone catabolic process |
| H | 0042802 | molecular_function | identical protein binding |
| H | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0005975 | biological_process | carbohydrate metabolic process |
| I | 0006000 | biological_process | fructose metabolic process |
| I | 0016829 | molecular_function | lyase activity |
| I | 0016832 | molecular_function | aldehyde-lyase activity |
| I | 0042182 | biological_process | ketone catabolic process |
| I | 0042802 | molecular_function | identical protein binding |
| I | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0005975 | biological_process | carbohydrate metabolic process |
| J | 0006000 | biological_process | fructose metabolic process |
| J | 0016829 | molecular_function | lyase activity |
| J | 0016832 | molecular_function | aldehyde-lyase activity |
| J | 0042182 | biological_process | ketone catabolic process |
| J | 0042802 | molecular_function | identical protein binding |
| J | 0097023 | molecular_function | fructose 6-phosphate aldolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue 4Y8 A 301 |
| Chain | Residue |
| A | ASP6 |
| A | ASN28 |
| A | LYS85 |
| A | LW2302 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue LW2 A 302 |
| Chain | Residue |
| A | SER166 |
| A | 4Y8301 |
| A | ASP6 |
| A | ASN28 |
| A | TYR131 |
| A | ASN133 |
| A | ARG134 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 303 |
| Chain | Residue |
| A | THR7 |
| A | LEU188 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | ALA62 |
| A | THR63 |
| A | THR64 |
| A | HOH445 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue LW2 B 302 |
| Chain | Residue |
| B | ASP6 |
| B | ASN28 |
| B | TYR131 |
| B | ARG134 |
| B | SER166 |
| B | 4Y8301 |
| B | HOH407 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| B | ALA62 |
| B | THR63 |
| B | THR64 |
| B | GLY67 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue LW2 C 302 |
| Chain | Residue |
| C | ASP6 |
| C | ASN28 |
| C | TYR131 |
| C | ASN133 |
| C | ARG134 |
| C | SER166 |
| C | PHE167 |
| C | LYS168 |
| C | 4Y8301 |
| C | HOH468 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue CL C 303 |
| Chain | Residue |
| C | ARG76 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue LW2 D 302 |
| Chain | Residue |
| D | ASP6 |
| D | ASN28 |
| D | TYR131 |
| D | ARG134 |
| D | SER166 |
| D | LYS168 |
| D | 4Y8301 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 303 |
| Chain | Residue |
| D | ALA62 |
| D | THR63 |
| D | THR64 |
| D | GLY67 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue LW2 E 302 |
| Chain | Residue |
| E | ASP6 |
| E | TYR131 |
| E | ASN133 |
| E | ARG134 |
| E | SER166 |
| E | LYS168 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 E 303 |
| Chain | Residue |
| E | ARG217 |
| E | THR218 |
| E | SER219 |
| F | GLN45 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue LW2 F 302 |
| Chain | Residue |
| F | ASP6 |
| F | TYR131 |
| F | ARG134 |
| F | SER166 |
| F | LYS168 |
| F | HOH419 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue CL F 303 |
| Chain | Residue |
| F | THR7 |
| F | THR31 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 F 304 |
| Chain | Residue |
| F | ALA62 |
| F | THR63 |
| F | THR64 |
| F | GLY67 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue LW1 G 302 |
| Chain | Residue |
| G | ASP6 |
| G | ARG134 |
| G | SER166 |
| G | HOH487 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 G 303 |
| Chain | Residue |
| G | ALA62 |
| G | THR63 |
| G | THR64 |
| G | GLY67 |
| G | HOH463 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue LW2 H 302 |
| Chain | Residue |
| H | ASP6 |
| H | TYR131 |
| H | ARG134 |
| H | SER166 |
| H | HOH470 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 H 303 |
| Chain | Residue |
| H | ALA62 |
| H | THR63 |
| H | THR64 |
| H | GLY67 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue LW2 I 302 |
| Chain | Residue |
| I | ASP6 |
| I | ARG134 |
| I | SER166 |
| I | LYS168 |
| site_id | AE3 |
| Number of Residues | 1 |
| Details | binding site for residue CL I 303 |
| Chain | Residue |
| I | ARG76 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 I 304 |
| Chain | Residue |
| I | ALA62 |
| I | THR63 |
| I | THR64 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue LW2 J 302 |
| Chain | Residue |
| J | ASN28 |
| J | TYR131 |
| J | ARG134 |
| J | SER166 |
| J | LYS168 |
| J | HOH436 |
| J | ASP6 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 J 303 |
| Chain | Residue |
| J | ALA62 |
| J | THR63 |
| J | THR64 |
| J | GLY67 |
| site_id | AE7 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide 4Y8 B 301 and LYS B 85 |
| Chain | Residue |
| B | ASP6 |
| B | THR26 |
| B | THR27 |
| B | ASN28 |
| B | PHE57 |
| B | ALA58 |
| B | THR59 |
| B | VAL60 |
| B | VAL83 |
| B | VAL84 |
| B | VAL86 |
| B | LEU107 |
| B | LW2302 |
| site_id | AE8 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide 4Y8 C 301 and LYS C 85 |
| Chain | Residue |
| C | ASP6 |
| C | THR27 |
| C | ASN28 |
| C | PHE57 |
| C | ALA58 |
| C | THR59 |
| C | VAL60 |
| C | VAL83 |
| C | VAL84 |
| C | VAL86 |
| C | LEU107 |
| C | THR109 |
| C | LW2302 |
| site_id | AE9 |
| Number of Residues | 11 |
| Details | binding site for Di-peptide 4Y8 D 301 and LYS D 85 |
| Chain | Residue |
| D | ASP6 |
| D | THR27 |
| D | ASN28 |
| D | ALA58 |
| D | THR59 |
| D | VAL60 |
| D | VAL83 |
| D | VAL84 |
| D | VAL86 |
| D | LEU107 |
| D | LW2302 |
| site_id | AF1 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide 4Y8 E 301 and LYS E 85 |
| Chain | Residue |
| E | ASP6 |
| E | THR26 |
| E | THR27 |
| E | ASN28 |
| E | PHE57 |
| E | ALA58 |
| E | THR59 |
| E | VAL60 |
| E | VAL83 |
| E | VAL84 |
| E | VAL86 |
| E | LEU107 |
| E | HOH466 |
| site_id | AF2 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide 4Y8 F 301 and LYS F 85 |
| Chain | Residue |
| F | ASP6 |
| F | THR26 |
| F | THR27 |
| F | ASN28 |
| F | PHE57 |
| F | ALA58 |
| F | THR59 |
| F | VAL60 |
| F | VAL83 |
| F | VAL84 |
| F | VAL86 |
| F | LEU107 |
| F | HOH422 |
| site_id | AF3 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide 4Y8 G 301 and LYS G 85 |
| Chain | Residue |
| G | ASP6 |
| G | THR26 |
| G | THR27 |
| G | ASN28 |
| G | ALA58 |
| G | THR59 |
| G | VAL60 |
| G | VAL83 |
| G | VAL84 |
| G | VAL86 |
| G | LEU107 |
| G | HOH437 |
| site_id | AF4 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide 4Y8 H 301 and LYS H 85 |
| Chain | Residue |
| H | ASP6 |
| H | THR26 |
| H | THR27 |
| H | ASN28 |
| H | ALA58 |
| H | THR59 |
| H | VAL60 |
| H | VAL83 |
| H | VAL84 |
| H | VAL86 |
| H | LEU107 |
| H | THR109 |
| H | HOH442 |
| site_id | AF5 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide 4Y8 I 301 and LYS I 85 |
| Chain | Residue |
| I | ASP6 |
| I | THR26 |
| I | THR27 |
| I | ASN28 |
| I | ALA58 |
| I | THR59 |
| I | VAL60 |
| I | VAL83 |
| I | VAL84 |
| I | VAL86 |
| I | LEU107 |
| I | HOH418 |
| site_id | AF6 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide 4Y8 J 301 and LYS J 85 |
| Chain | Residue |
| J | ASP6 |
| J | THR26 |
| J | THR27 |
| J | ASN28 |
| J | PHE57 |
| J | ALA58 |
| J | THR59 |
| J | VAL60 |
| J | VAL84 |
| J | VAL86 |
| J | LEU107 |
| J | THR109 |
Functional Information from PROSITE/UniProt
| site_id | PS00958 |
| Number of Residues | 18 |
| Details | TRANSALDOLASE_2 Transaldolase active site. IvVKVPvTaEGLaAiKmL |
| Chain | Residue | Details |
| A | ILE82-LEU99 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Active site: {"description":"Schiff-base intermediate with substrate","evidences":[{"source":"PubMed","id":"11120740","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12051943","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
