5ZNJ
Crystal structure of a bacterial ProRS with ligands
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proline--tRNA ligase | polymer | 567 | 63938.0 | 1 | UniProt (A0A227M497) | Staphylococcus aureus | Prolyl-tRNA synthetase,ProRS |
| 2 | B (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 3 | C (A) | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one | non-polymer | 414.7 | 1 | Chemie (HFG) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | G (A) | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence modifications
A: 1 - 567 (UniProt: A0A227M497)
| PDB | External Database | Details |
|---|---|---|
| Thr 230 | Ala 230 | see sequence details |
| Ala 278 | Val 278 | see sequence details |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 63938.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1132.2 | |
| All* | Total formula weight | 65070.2 |
