5ZM6
Crystal structure of ORP1-ORD in complex with PI(4,5)P2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Oxysterol-binding protein-related protein 1 | polymer | 436 | 50528.3 | 2 | UniProt (Q9BXW6) Pfam (PF01237) | Homo sapiens (Human) | OSBP-related protein 1 |
| 2 | C, E (A, B) | [(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{S},5~{S},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl] icosa-5,8,11,14-tetraenoate | non-polymer | 1047.1 | 2 | Chemie (IEP) | |||
| 3 | D, F (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
A, B: 524 - 950 (UniProt: Q9BXW6)
| PDB | External Database | Details |
|---|---|---|
| Met 523 | - | initiating methionine |
| Leu 951 | - | expression tag |
| Glu 952 | - | expression tag |
| His 953 | - | expression tag |
| His 954 | - | expression tag |
| His 955 | - | expression tag |
| His 956 | - | expression tag |
| His 957 | - | expression tag |
| His 958 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 101056.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2212.3 | |
| All* | Total formula weight | 103268.9 |
