5ZM6

Crystal structure of ORP1-ORD in complex with PI(4,5)P2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Oxysterol-binding protein-related protein 1	polymer	436	50528.3	2	UniProt (Q9BXW6) Pfam (PF01237) In PDB	Homo sapiens (Human)	OSBP-related protein 1
2	A, B	[(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{S},5~{S},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl] icosa-5,8,11,14-tetraenoate	non-polymer		1047.1	2	Chemie (IEP)
3	A, B	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
4		water	water		18.0	28	Chemie (HOH)

Sequence modifications

A, B: 524 - 950 (UniProt: Q9BXW6)

PDB	External Database	Details
Met 523	-	initiating methionine
Leu 951	-	expression tag
Glu 952	-	expression tag
His 953	-	expression tag
His 954	-	expression tag
His 955	-	expression tag
His 956	-	expression tag
His 957	-	expression tag
His 958	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	101056.6
Non-Polymers*	Number of molecules	4
	Total formula weight	2212.3
All*	Total formula weight	103268.9

*Water molecules are not included.