5ZBU
Crystal Structure of PA-TM-RING E3 ligase RNF13 RING domain in complex with E2~Ub
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (C, B) | Ubiquitin-conjugating enzyme E2 D2 | polymer | 148 | 16838.3 | 2 | UniProt (P62837) Pfam (PF00179) | Homo sapiens (Human) | (E3-independent) E2 ubiquitin-conjugating enzyme D2,E2 ubiquitin-conjugating enzyme D2,Ubiquitin carrier protein D2,Ubiquitin-conjugating enzyme E2(17)KB 2,Ubiquitin-conjugating enzyme E2-17 kDa 2,Ubiquitin-protein ligase D2,p53-regulated ubiquitin-conjugating enzyme 1 |
| 2 | C, D (A, D) | E3 ubiquitin-protein ligase RNF13 | polymer | 76 | 8840.5 | 2 | UniProt (O43567) Pfam (PF13639) | Homo sapiens (Human) | RING finger protein 13,RING-type E3 ubiquitin transferase RNF13 |
| 3 | E (E) | Ubiquitin | polymer | 76 | 8576.8 | 1 | UniProt (P0CG47) Pfam (PF00240) | Homo sapiens (Human) | |
| 4 | F, G, H, I (A, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | J, K, L, M (C, A, D, E) | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
C, B: 1 - 147 (UniProt: P62837)
A, D: 216 - 290 (UniProt: O43567)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Lys 85 | Cys 85 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 215 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 59934.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 60196.1 |
