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5Z94

Crystal Structure of SIRT3 in complex with H3K4bhb peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
NAD-dependent protein deacetylase sirtuin-3, mitochondrialpolymer28331427.22UniProt (Q9NTG7)
Pfam (PF02146)
Homo sapiens (Human)hSIRT3,Regulatory protein SIR2 homolog 3,SIR2-like protein 3
2C, D
(C, D)
Gene for histone H3 (germline gene)polymer151650.92UniProt (V9H1G0)Homo sapiens
3E, J
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
4F, G, K, N
(A, B, D)
GLYCEROLnon-polymer92.14Chemie (GOL)
5H, L
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
6I, M
(A, B)
CITRIC ACIDnon-polymer192.12Chemie (CIT)
7O, P, Q, R
(A, B, C, D)
waterwater18.0507Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight66156.1
Non-Polymers*Number of molecules10
Total formula weight1075.6
All*Total formula weight67231.6
*Water molecules are not included.

248636

PDB entries from 2026-02-04

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